How Metabolites from C. acnes Improve Barrier Function

Oct 3rd, 2023

C. acnes induced a large increase in lipids such as triglycerides, ceramides, cholesterol and free fatty acids.

C. acnes induced a large increase in lipids such as triglycerides, ceramides, cholesterol and free fatty acids.

maxbelchenko

A study published in Microbiology has uncovered the ability of Cutibacterium acnes metabolites to support the skin barrier.

Per the article abstract, researchers analyzed the response of human keratinocytes to different commensal bacteria and observed that C. acnes induced a large increase in lipids such as triglycerides, ceramides, cholesterol and free fatty acids. This increase improved barrier functions including antimicrobial activity, diffusion between cells and TEWL.

Additional analysis showed this increase was brought about by the short-chain fatty acids produced by C. acnes and was dependent on an increased expression of several lipid synthesis genes.

See the full paper for additional details.

See related: 6 Ways Staphylococcus Hominis Protects Skin Through Quorum Sensing

Reversing Sun Damage & Signs of Aging Caused by UV Exposure with Laser Therapy

Reversing Sun Damage & Signs of Aging Caused by UV Exposure with Laser Therapy

In the ever-evolving world of dermatology, the battle against skin aging and sun damage remains a paramount concern. Enter Reverse® by Aerolase, a groundbreaking approach to laser therapy that has revolutionized skin rejuvenation.

Doctor, dermatologist, hands examines a birthmark of patient. Checking benign moles

Skin Cancer Innovations: New Detection Device & Possible Vaccine for Melanoma

Vaccines and devices designed to identify and combat skin cancer are currently in the clinical trial phases, including research from DermaSensor, Moderna, Merck and more.

semaglutide ozempic injections for blood sugar/weight loss

FDA Cracks Down on Ozempic Knockoffs

The FDA issued warning letters to two companies selling "highly purified peptides," accusing the companies of misleading consumers through their sales of highly purified peptides.

Photo of beautiful woman getting mesotherapy treatment in face

5 Insights into Patient Spending Habits during Holiday Seasons

Qsight Aesthetics Tracker reports there is a peak demand for neurotoxins, light wave therapy and professional skin care during Q4, with consistent spending across generational gaps.

The research conducted at the center will focus on applicable scientific discoveries to advance allergy science and develop topical innovations to address skin conditions, per the organizations.

Clinique x Mount Sinai Tackle Aging, Eczema & Allergies for Actionable Innovation

Research will comprise all ages, genders, races and ethnicities, and will "investigate the effects of factors such as diet, exercise, and stress on the skin of healthy people."

Girl At Spa Salon. Beautician Applying White Cosmetic Powder

Medical Aesthetic Industry Projects to Grow 14% Annually Through 2026

McKinsey & Company detailed potential growth opportunities and an overall bright future for the medical aesthetics industry in its "Life Sciences Practice."

Gay queer asian man non-binary influencer sitting easy at home sofa. Asia non binary LGBT young guy adult two people happy relax

Acne Interferes with Gender Expressions in Transgender Patients

A January 2024 study in JAMA Dermatology found that acne can interfere with desired gender expression and contribute to negative stigmas and stereotypes towards gender-diverse individuals.

Close up of a happy and relaxed young woman with perfect olive skin fixing her wavy black hair isolated on white

Study Demonstrates Effectiveness of MatriDerm Collagen-Elastin Template

The study from the University Medical Center in Dresden, Germany, highlights MatriDerm's role in reducing operating room time, avoiding flap surgery in up to 80% of cases and eliminating donor site morbidities associated with traditional flap procedures.

Teen girl with acne problem applying cream near mirror in bathroom

AAD Releases Updated Guidelines for Management of Acne Vulgaris

The American Academy of Dermatology made strong recommendations for topical benzoyl peroxide, retinoids, and/or antibiotics and their fixed-dose combinations and for oral doxycycline.

89% of readers are considering adding exosome therapy to their service offerings! Here are the top ten exosome treatment advances shaping the future of aesthetics.

Top 10 Exosome Treatment Advances Taking Over Aesthetics [Survey Results]

89% of readers are considering adding exosome therapy to their service offerings! Here are the top ten exosome treatment advances shaping the future of aesthetics.

In sunglasses. Young passenger woman in yellow clothes is flying in the plane

Patients are Going Abroad to Address Loose Skin and 'Ozempic Face' Concerns

Rapid weight loss can sometimes increase signs of aging, now referred to as "Ozempic Face" due to the popularity of the drug. Patients are opting to address these issues overseas, reflecting the growing medical tourism trend.

Female doctor talking with colleagues through a video call with a laptop in the consultation.

Telehealth in Medical Aesthetics Expands to Medspa & GLP-1 Treatments

The expansion of telehealth across the medical industry has altered the consultation process and led to new programs that integrate telehealth into their aesthetic offerings, including a new GLP-1 therapy program and at-home med spas.